What are the Potential Risks and Adverse Effects of CSFs?
While CSFs are generally well-tolerated, they can have some adverse effects. Common side effects include bone pain, fever, and injection site reactions. Rarely, they can cause more serious effects such as splenic rupture, acute respiratory distress syndrome (ARDS), and the potential exacerbation of certain types of cancer due to the stimulation of cell proliferation. Therefore, careful monitoring is necessary when administering CSFs, especially in patients with a history of hematologic malignancies.