What are the Potential Toxic Effects of Nucleobase Alterations?
Alterations in nucleobases, such as mutations, can lead to significant health risks. These alterations can be caused by various factors, including chemical mutagens, radiation, and environmental pollutants. Such changes may result in carcinogenesis, where mutations accumulate and disrupt normal cell function, potentially leading to cancer. Additionally, nucleobase modifications can lead to genetic disorders and impact cellular processes such as replication and repair.