To minimize the risk of toxicity, careful dosing of vincristine is essential. The dose is often adjusted based on the patient's body surface area and liver function. Monitoring for signs of neurotoxicity, such as changes in sensation or motor function, is critical during treatment.
It is also important to ensure that vincristine is administered intravenously and not intrathecally. Clear labeling and separate storage of intrathecal and intravenous chemotherapy drugs can prevent accidental intrathecal administration.
