What are the Toxicological Concerns Associated with Purines?
Purine metabolism can lead to toxicological concerns primarily when there is an overproduction or reduced excretion of uric acid. Elevated levels of uric acid in the blood, a condition known as hyperuricemia, can lead to gout, a form of inflammatory arthritis. Moreover, excessive uric acid can form crystals in the joints and tissues, causing intense pain and inflammation.