What are the toxicological concerns with antidepressants?
Toxicological concerns with antidepressants primarily revolve around overdose and potential interactions with other substances. Key toxicological issues include:
Cardiotoxicity - Particularly with TCAs, which can lead to arrhythmias and other heart issues. Serotonin Syndrome - A potentially life-threatening condition caused by excessive serotonin levels, often due to interactions with other serotonergic drugs. Hepatotoxicity - Some antidepressants can cause liver damage, especially with long-term use. Neurotoxicity - High doses can lead to seizures and other neurological complications.
