What role does pharmacogenomics play in antidepressant toxicity?
Pharmacogenomics is the study of how genes affect a person's response to drugs. Genetic variations can influence the metabolism, efficacy, and toxicity of antidepressants. For instance, variations in the CYP450 enzyme system can affect how quickly a drug is metabolized, impacting both therapeutic outcomes and the risk of toxicity. Personalized medicine approaches can help tailor antidepressant therapy to minimize adverse effects and improve efficacy.
