What are the Toxicological Concerns with Formic Acid?
The primary toxicological concern with formic acid is its potential to cause metabolic acidosis, which can disrupt normal physiological processes. In the context of methanol poisoning, formic acid accumulation is a significant risk factor for ocular toxicity and central nervous system depression. It acts as an inhibitor of cytochrome c oxidase, leading to impaired cellular respiration and energy production.
