What are the Toxicological Implications of LDL Cholesterol?
High LDL cholesterol levels can act synergistically with certain toxic agents, such as heavy metals and tobacco smoke, to amplify vascular damage. These interactions can accelerate the progression of atherosclerosis by promoting lipid oxidation and endothelial dysfunction. This synergistic effect is a significant concern in toxicology, as it underscores the need for comprehensive risk assessment of chemical exposures in individuals with elevated LDL levels.