Bleeding complications can result from exposure to specific toxic agents that interfere with the coagulation cascade or damage blood vessels. Common causes include:
- Anticoagulant Rodenticides: These substances inhibit vitamin K-dependent clotting factors, leading to severe bleeding. - Heparin and Warfarin Overdose: Overmedication or interaction with other drugs can exacerbate anticoagulant effects. - Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): These can cause gastrointestinal bleeding by inhibiting prostaglandins. - Heavy Metals: Some heavy metals, like arsenic, can disrupt vascular integrity. - Snake Venom: Certain snake bites introduce toxins that impair blood clotting.
