What Causes Chemotherapy-Induced Nausea and Vomiting?
CINV is primarily caused by the chemotherapeutic agents used to treat cancer. These drugs can irritate the gastrointestinal tract and stimulate the vomiting center in the brain. The process involves several pathways, including the release of neurotransmitters like serotonin and substance P, which activate receptors in the central and peripheral nervous systems, triggering nausea and vomiting.
