Serotonin syndrome is typically caused by the use of multiple serotonergic agents or overdosing on a single serotonergic drug. Common culprits include selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), monoamine oxidase inhibitors (MAOIs), and certain pain medications like tramadol and fentanyl. Recreational drugs such as MDMA (ecstasy) and other amphetamines can also induce serotonin syndrome.
