Serotonin toxicity, also known as serotonin syndrome, occurs when there is an excess of serotonin in the brain. This can be caused by the use of certain medications, such as selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), MAO inhibitors, and even some over-the-counter supplements. Additionally, drug interactions, overdose, or the concomitant use of multiple serotonergic agents can precipitate this condition.