Treatment of hepatotoxicity depends on the underlying cause and severity of liver damage. General strategies include: - Discontinuation of the Causative Agent: Stopping the use of the hepatotoxic drug or substance is crucial. - Supportive Care: Providing adequate hydration, nutrition, and monitoring of liver function. - Use of Antioxidants: Agents like N-acetylcysteine can be used to treat acetaminophen overdose by replenishing glutathione levels and reducing oxidative stress. - Liver Transplantation: In cases of severe liver failure, a liver transplant may be necessary.