Several factors can affect how efficiently a substance is eliminated from the body:
Age: Younger individuals and the elderly may have altered elimination rates due to immature or declining organ function. Genetics: Genetic variations can influence metabolic enzyme activity, impacting how fast or slow a substance is metabolized and eliminated. Health Status: Conditions like kidney or liver disease can impair the elimination processes. Drug Interactions: Certain drugs can inhibit or induce metabolic enzymes, affecting the elimination of other substances. Physicochemical Properties: The chemical nature of a substance (e.g., size, polarity) can determine its elimination route and rate.
