What Factors Contribute to Variability in Sensitivity?
Several factors contribute to the variability in human sensitivity to toxic substances. These include genetic differences, age, sex, health status, and environmental influences. Genetic polymorphisms, for instance, can affect metabolic pathways, leading to variations in how individuals process toxins. Age can influence sensitivity, as children and the elderly may have differing metabolic capabilities compared to adults. Similarly, sex-based differences can alter hormonal regulation and metabolic rates, impacting sensitivity levels.
