Thyroid peroxidase (TPO) is an enzyme crucial for the synthesis of thyroid hormones. It is found in the thyroid gland and catalyzes the iodination of tyrosine residues in thyroglobulin, a process essential for the production of thyroxine (T4) and triiodothyronine (T3). These hormones are vital for regulating metabolism, growth, and development. Impairment or inhibition of TPO can lead to significant health issues, making it a critical focus in toxicology.
