Several factors can influence the intake of a substance, including its physical and chemical properties, the route of exposure, and the duration of exposure. For example, substances that are highly soluble in lipids are more likely to be absorbed through the skin, while volatile compounds are more readily inhaled. The age, sex, and health status of an individual can also affect how substances are absorbed and processed by the body. Additionally, interactions with other chemicals can modify the intake and toxicity of a substance.
