distribution of toxins

What Factors Influence Toxin Distribution?

Several factors influence the distribution of toxins, including:
Blood Flow: Tissues with high blood flow, such as the liver, kidneys, and brain, tend to receive toxins more rapidly.
Lipid Solubility: Lipid-soluble toxins can easily cross cell membranes and accumulate in fatty tissues.
Protein Binding: Toxins that bind to plasma proteins may have a prolonged presence in the bloodstream, affecting their distribution.
Cellular Transport Mechanisms: Specific transport proteins can facilitate or restrict the passage of toxins across cell membranes.

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