Several factors influence the distribution of toxins, including:
Blood Flow: Tissues with high blood flow, such as the liver, kidneys, and brain, tend to receive toxins more rapidly. Lipid Solubility: Lipid-soluble toxins can easily cross cell membranes and accumulate in fatty tissues. Protein Binding: Toxins that bind to plasma proteins may have a prolonged presence in the bloodstream, affecting their distribution. Cellular Transport Mechanisms: Specific transport proteins can facilitate or restrict the passage of toxins across cell membranes.