8-OHdG is a modified form of the nucleoside deoxyguanosine, which results from the oxidative damage of DNA. It is one of the most common products of DNA oxidation and serves as a reliable marker for cellular oxidative stress. The presence of 8-OHdG can indicate the level of oxidative stress in cells, which is often linked to various diseases, including cancer, cardiovascular diseases, and neurodegenerative disorders.