Several factors can influence the levels of 8-OHdG in the body. Lifestyle choices, such as diet rich in antioxidants, can decrease oxidative stress, thereby reducing 8-OHdG levels. Conversely, factors like smoking, excessive alcohol consumption, and exposure to environmental pollutants or ionizing radiation can increase oxidative damage, leading to elevated 8-OHdG. Genetic predispositions and underlying health conditions, such as inflammation or metabolic disorders, also play a role in modulating 8-OHdG levels.
