What are the Implications of Elevated 8-OHdG Levels?
Elevated levels of 8-OHdG are often associated with increased risk of diseases. In cancer research, high 8-OHdG levels have been linked to tumorigenesis due to its role in DNA mutations. In cardiovascular health, oxidative DNA damage marked by 8-OHdG can contribute to the development of atherosclerosis. Furthermore, in neurological studies, increased 8-OHdG levels have been observed in conditions like Alzheimerâs and Parkinsonâs diseases, highlighting its potential as a diagnostic tool and target for therapeutic interventions.
