ADP ribosylation is a post-translational modification involving the addition of ADP-ribose units to proteins. This modification is catalyzed by a family of enzymes known as ADP-ribosyltransferases. The process can play critical roles in cellular processes such as DNA repair, signal transduction, and transcriptional regulation. In the context of Toxicology, ADP ribosylation is significant due to its involvement in the mechanism of action of certain toxins and its potential implications in cellular damage and repair mechanisms.
