Gorlin Syndrome, also known as Nevoid Basal Cell Carcinoma Syndrome (NBCCS), is a genetic disorder that predisposes individuals to the development of multiple basal cell carcinomas, jaw cysts, and skeletal abnormalities. It is caused by mutations in the PTCH1 gene, which plays a critical role in the Hedgehog signaling pathway. This pathway is crucial for normal embryonic development and cellular growth.
