non linear pharmacokinetics

What is Non-Linear Pharmacokinetics?

Non-linear pharmacokinetics refers to the phenomenon where the change in drug concentration does not directly correlate with the dose administered. This deviation from the linear pharmacokinetic model can occur due to various factors and is crucial in the field of toxicology as it can significantly impact drug safety and efficacy. In contrast to linear pharmacokinetics, where parameters like clearance and half-life remain constant, non-linear pharmacokinetics can result in unpredictable drug behavior at different concentration levels.

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