What is Pharmacogenomics and How is it Related to Gene Products?
Pharmacogenomics is the study of how genes affect a person's response to drugs. It involves understanding the role of gene products in drug metabolism and toxicity. Variations in genes encoding drug-metabolizing enzymes, transporters, and receptors can lead to differences in drug efficacy and safety. For instance, polymorphisms in the gene encoding the enzyme thiopurine S-methyltransferase (TPMT) affect the metabolism and toxicity of thiopurine drugs used in chemotherapy.
