Phosphoproteomics is a subset of proteomics that specifically focuses on the comprehensive analysis of phosphorylation, a post-translational modification critical for regulating protein function. Phosphorylation involves the addition of a phosphate group, often to serine, threonine, or tyrosine residues, and plays a crucial role in cellular signaling pathways. In toxicology, phosphoproteomics helps to elucidate how toxic agents alter signaling pathways and affect cellular responses.
