What is the Connection Between NK1 Receptors and Neurotoxicity?
Neurotoxicity refers to damage to the nervous system caused by exposure to natural or synthetic toxic substances. NK1 receptors are involved in neurotoxic effects as they can influence neuronal survival and apoptosis. The overstimulation of NK1 receptors by substance P has been linked to increased neural damage and oxidative stress. Investigating NK1 receptor antagonists could therefore be a promising approach to protect against neurotoxic effects in cases of exposure to neurotoxic agents.
