Mitigating the effects of 8-oxoguanine involves reducing oxidative stress through lifestyle modifications, dietary antioxidants, and pharmacological interventions. Antioxidants like vitamin C, vitamin E, and flavonoids can neutralize ROS and prevent oxidative DNA damage. Additionally, enhancing the activity of DNA repair pathways through pharmacological agents or gene therapy could provide therapeutic benefits in reducing the mutagenic consequences of 8-oxoguanine.
