The future of GWAS in toxicology is promising, with advancements in genomic technologies and bioinformatics poised to enhance their efficacy. Integration with other omics approaches, such as transcriptomics and metabolomics, can provide a more comprehensive understanding of toxicological responses. Additionally, the development of better statistical methods and larger, more diverse cohorts will improve the power and applicability of GWAS findings.
In conclusion, GWAS offer powerful tools for elucidating the genetic underpinnings of toxicological responses. By addressing current challenges and ethical considerations, these studies can significantly contribute to personalized medicine, public health, and safety regulations in toxicology.