What is the Impact of Genetic Variation on Metabolic Adaptation?
Genetic variation plays a crucial role in metabolic adaptation. Polymorphisms in genes encoding metabolic enzymes can lead to differences in how individuals metabolize xenobiotics. For example, variations in the genes encoding glutathione-S-transferases or N-acetyltransferases can affect the rate of biotransformation, potentially influencing susceptibility to certain chemicals and drugs.
