lowest observed adverse effect level

What is the Lowest Observed Adverse Effect Level (LOAEL)?

The Lowest Observed Adverse Effect Level (LOAEL) is a critical concept in toxicology and risk assessment. It refers to the smallest concentration or amount of a substance, found by experimentation, that causes a statistically or biologically significant increase in the frequency or severity of adverse effects. These effects are observed in the exposed population compared to an appropriate control group.

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