What is the Role of Skin Metabolism in Toxicology?
The skin is not only a barrier but also a site for biotransformation of chemicals. Enzymes present in the skin can metabolize xenobiotics, potentially activating or detoxifying them. This metabolic capability is significant in toxicology, as it influences the local and systemic effects of chemicals. Understanding skin metabolism is essential for predicting the outcomes of exposure and for developing effective therapeutic interventions.
