What is the Significance of Enzymes in Toxicology?
Enzymes are proteins that catalyze biochemical reactions and are critical in the metabolism of toxicants. Enzymes such as cytochrome P450 play a significant role in the biotransformation of toxic substances, often converting them into more water-soluble forms for excretion. However, this process can sometimes produce more toxic or reactive intermediates, influencing the overall toxicity profile of the substance.