Currently, there is no specific antidote for ciguatera poisoning. Treatment is mainly supportive and symptomatic. Management may include rehydration for gastrointestinal symptoms, analgesics for pain, and medications like amitriptyline for neurological symptoms. In severe cases, intravenous fluids and cardiovascular support may be necessary. Although some studies have suggested that intravenous mannitol can alleviate symptoms, its efficacy remains controversial, and more research is needed to clarify its role.
