How Do HepG2 Cells Contribute to Drug Development?
In drug development, HepG2 cells are used to screen potential drug candidates for hepatotoxicity early in the development process. This helps to identify and eliminate compounds that might cause liver damage before clinical trials, thereby reducing the risk of adverse effects in humans. HepG2 cells also provide data on the metabolism and bioactivation of drugs, which is crucial for understanding their pharmacokinetics and potential side effects.
