What Methods Are Used to Study Metaphase Disruption?
Scientists employ several methods to study the effects of toxicants on metaphase. Cytogenetic assays, such as the chromosome aberration test, help identify structural chromosome changes. The micronucleus test is another technique that detects chromosomal fragments or whole chromosomes that fail to incorporate into daughter nuclei. These assays are invaluable for assessing the genotoxic potential of chemical substances.
