Omics technologies, including genomics, transcriptomics, proteomics, and metabolomics, are transforming toxicology by enabling a comprehensive analysis of biological responses to toxicants. Transcriptomics, in particular, focuses on the study of RNA transcripts produced by the genome under specific circumstances. By leveraging these technologies, researchers can identify gene signatures associated with toxicant exposure, understand complex biological networks, and predict the potential toxicity of new compounds.