What Techniques are Used in High Resolution Toxicology?
Several advanced techniques are employed in high-resolution toxicology, including:
1. High-Resolution Mass Spectrometry (HRMS): This technique offers excellent mass accuracy and resolution, facilitating the identification of unknown compounds and the quantification of known toxicants with high precision. 2. Nuclear Magnetic Resonance (NMR) Spectroscopy: NMR provides detailed information about the molecular structure of toxic substances, aiding in their identification and characterization. 3. Chromatography: Techniques such as High-Performance Liquid Chromatography (HPLC) and Gas Chromatography (GC) coupled with high-resolution detectors are widely used for separating and analyzing complex mixtures. 4. Fourier Transform Infrared (FTIR) Spectroscopy: FTIR is used to obtain the infrared spectrum of absorption or emission of a solid, liquid, or gas, providing molecular-level information about toxicants.