When is Mechanical Ventilation Indicated in Toxicology?
Mechanical ventilation is often indicated in cases of severe poisoning where respiratory failure is imminent or has already occurred. Common scenarios include: - Central nervous system depressants: Overdoses of substances like opioids, benzodiazepines, and barbiturates can lead to respiratory depression. - Aspiration: Patients who have ingested toxic substances may aspirate, leading to compromised lung function. - Neuromuscular toxins: Exposure to toxins like organophosphates can result in respiratory muscle paralysis. - Hypoxia: Toxins such as carbon monoxide can impair the blood's ability to carry oxygen. - Severe metabolic acidosis: Conditions induced by substances like methanol or ethylene glycol can necessitate mechanical ventilation.
