activation of nuclear receptors

Which Nuclear Receptors are Commonly Studied in Toxicology?

Some of the most commonly studied nuclear receptors in toxicology include:
Aryl Hydrocarbon Receptor (AhR): Involved in the metabolism of xenobiotics and mediates the toxic effects of dioxins.
Peroxisome Proliferator-Activated Receptors (PPARs): Play a role in lipid metabolism and are targets for drugs used to treat hyperlipidemia and diabetes.
Estrogen Receptors (ERs): Mediate the effects of estrogens and are important in reproductive health.
Androgen Receptors (ARs): Mediate the effects of androgens and are important in male reproductive health.
Glucocorticoid Receptors (GRs): Involved in the stress response and immune system regulation.

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