How is the Activation of Nuclear Receptors Studied?
The activation of nuclear receptors is studied using a variety of methods, including:
In Vitro Assays: Cell-based assays to study the binding and activation of nuclear receptors by various ligands. Reporter Gene Assays: Used to measure the transcriptional activity of nuclear receptors in response to different compounds. Animal Models: Transgenic animals are used to study the physiological and toxicological effects of nuclear receptor activation. Molecular Docking: Computational methods to predict how different ligands interact with nuclear receptors.