Certain tissues are more susceptible to toxic damage due to their high metabolic activity, blood flow, or specific functions. The liver, for example, is a primary site for detoxification and is frequently affected by toxicants, resulting in conditions like hepatitis or cirrhosis. The kidneys, essential for excreting waste, are also vulnerable, leading to nephrotoxicity. The nervous system can suffer neurotoxicity due to its complex structure and limited regenerative capacity.
