Why Are Elderly Patients More Susceptible to Toxicity?
Elderly patients are more susceptible to toxicity due to several factors. Polypharmacy, the concurrent use of multiple medications, increases the risk of adverse drug interactions and cumulative toxic effects. Age-related decline in organ function can lead to accumulation of drugs or toxicants in the body. Furthermore, comorbidities common in the elderly can exacerbate the toxic effects or complicate the clinical presentation.