Local conditions are critical in toxicology because they can significantly modify the ADME (Absorption, Distribution, Metabolism, and Excretion) processes of toxic substances. For instance, climatic conditions such as temperature and humidity can influence the evaporation and dispersion of volatile chemicals. Furthermore, cultural practices such as diet and traditional medicine can lead to unique exposure scenarios that are different from those observed in other regions. Understanding these conditions is essential for accurate risk assessment and for developing effective public health interventions.
