The significance of iodination in toxicology stems from its impact on thyroid function and the potential for iodine toxicity. Iodine deficiency can lead to disorders such as goiter and hypothyroidism, affecting millions globally. Conversely, excessive iodine intake can result in hyperthyroidism or thyroiditis. Therefore, the balance of iodine levels is crucial for maintaining health, and toxicologists study this balance to prevent disorders associated with iodine imbalance.