Why is the Intrinsic Pathway Important in Toxicology?
In toxicology, the intrinsic pathway is crucial for understanding how cells respond to toxic insults. It serves as a defense mechanism to eliminate cells that have sustained irreparable damage, thus preventing the propagation of mutations or other defects. Moreover, dysregulation of the intrinsic pathway can lead to diseases such as cancer, where cells evade apoptosis, or neurodegenerative disorders, where there is excessive apoptosis.