Can the Intrinsic Pathway Be Targeted for Therapeutic Purposes?
Yes, targeting the intrinsic pathway holds potential for therapeutic interventions, particularly in cancer treatment. Modulating the activity of Bcl-2 family proteins or restoring the function of p53 can sensitize cancer cells to apoptosis, enhancing the efficacy of chemotherapeutic agents. Similarly, in diseases characterized by excessive apoptosis, strategies to inhibit the intrinsic pathway may help in preserving cell viability.
