Are There Any Known Toxicants that Affect the Wnt Pathway?
Yes, several toxicants are known to interact with the Wnt pathway. Arsenic, a well-known environmental toxin, has been shown to alter Wnt signaling, contributing to skin and bladder cancers. Similarly, polychlorinated biphenyls (PCBs) can disrupt Wnt signaling, potentially leading to developmental and reproductive toxicity.
