Given their critical role in detoxification, GSTs are being studied for their potential therapeutic applications. By modulating GST activity, it may be possible to enhance the detoxification of harmful compounds or improve the therapeutic index of certain drugs. In addition, GSTs are used as biomarkers for exposure to environmental toxins and as targets for drug development. Researchers are investigating ways to exploit GST pathways to develop novel treatments for diseases associated with oxidative stress and chemical toxicity.