Are There Therapeutic Interventions Targeting CYP2E1?
Given its role in mediating toxicity, there is interest in developing inhibitors of CYP2E1 as potential therapeutic agents. Inhibitors like disulfiram have been explored for their ability to mitigate oxidative stress and reduce liver damage. However, targeting CYP2E1 requires careful consideration due to its involvement in essential metabolic processes. Thus, therapeutic strategies need to balance inhibition of harmful pathways with preservation of its physiological functions.
